AN EVALUATION OF A SVA RETROTRANSPOSON IN THE FUS PROMOTER AS A TRANSCRIPTIONAL REGULATOR AND ITS ASSOCIATION TO ALS.

An evaluation of a SVA retrotransposon in the FUS promoter as a transcriptional regulator and its association to ALS.

Genetic mutations of FUS have been linked to many diseases including Amyotrophic Lateral Sclerosis (ALS) and Frontotemporal Lobar Degeneration.A primate specific and polymorphic retrotransposon of the SINE-VNTR-Alu (SVA) family is present upstream of the FUS gene.Here we have demonstrated that this retrotransposon frog castanet can act as a classic

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Characteristics of overlying strata movement and control technology of final mining section in fully mechanized mining face with double retracting passage

In order to solve the problems of severe mining pressure during the final mining of fully mechanized mining face in Jinjie Coal Mine, large deformation of surrounding rock in the withdrawal channel and difficult to control, based on the background of 31115 working face mining in Jinjie Coal Mine, a combination luvy duvy ice cream of theoretical ana

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